Francis is a French and English surname of Latin origin. Notable people with the surname include:
Alun Francis (born 1943), Welsh conductorAnne Francis (1930-2011), was an American actressArlene Francis (1907-2001), American actressBarrington Francis, Jamaican/Canadian boxer of the 1980s and '90sBlack Francis (born 1965), American MusicianClare Francis (born 1946), British authorConnie Francis (born 1938), American pop singerDavid Rowland Francis (1850–1927), American politician, Mayor of Saint Louis, Governor of Missouri, U.S. Secretary of the InteriorDamien Francis, (born 1979), English-born Jamaican footballerDanusia Francis, (born 1994), British gymnastDick Francis (1920-2010), British jockey-turned-novelistEddie Francis, (born 1974), Canadian politicianFreddie Francis (1917-2007), English cinematographer and film directorJane Francis, Winner of Polar Medal, 2002Genie Francis (born 1962), ActressGerry Francis (born 1951), English footballer and managerJames Francis (1819-1884), Australian colonial politicianJeff Francis, Major League Baseball pitcherJoseph Francis (disambiguation), several people named Joe or Joseph FrancisKay Francis (1905-1968), American actressKevin Francis (disambiguation), several people named Kevin FrancisK. T. Francis (1939–2013), Sri Lankan cricket umpireLeigh Francis (born 1974), British comedianLeslie Francis, American philosopherMark Francis (disambiguation)Melissa Francis (born 1972), American television journalist and former child actressMichael Kpakala Francis (1936–2013), Liberian Roman Catholic archbishopNorman Francis (born 1931), President of Xavier University of LouisianaRanganathan Francis (born 1920), Indian hockey playerRobert Francis (barrister) (born 1950), British barrister specialising in medical lawRon Francis (born 1963), Canadian professional ice hockey centermanRoy Francis, British rugby league footballer and coachSage Francis (born 1977), hip-hop artistSam Francis, (1923-1994), American painter and printmakerSam Francis, American football playerSamuel Kensinger Francis, Fitness trainerSamuel T. Francis (1947–2005), American columnistSteve Francis (born 1977), American professional basketball playerThomas Francis, Jr. (1900-1969), American physician, virologist, and epidemiologistTrevor Francis (born 1954), English footballer