Frère is a French surname. Notable people with the surname include:
Albert Frère (born 1926), Belgian businessman
Bernard-Georges-François Frère (1764-1826), French general
Édouard Frère (1797–1874), French bookseller, archivist, scholar and biographer
Maurice Frère (died 1970), governor of the National Bank of Belgium
Paul Frère (1917–2008), Belgian racing driver and journalist
Pierre Edouard Frère (1819–1886), French painter
