Fotopoulos (Greek: Φωτόπουλος) or Photopoulos (sometimes for female persons it becomes: Fotopoulou or Photopoulou) is a Greek surname. Notable people with the surname include:
Danielle Fotopoulos (born 1976), soccer player, US women's national soccer team
George Fotopoulos, former head coach of the LSU women's soccer team
Helen Fotopoulos, Montreal city councillor
James Fotopoulos (born 1976), American independent filmmaker
Mimis Fotopoulos (1913-1986), Greek actor
Natalie Fotopoulos, American dance teacher who participated in FOX reality show, So You Think You Can Dance
Takis Fotopoulos (born 1940), Greek political writer and editor
Vassilis Photopoulos (1934-2007), Greek painter and film director
