Formate dehydrogenase (cytochrome c 553)

In enzymology, a formate dehydrogenase (cytochrome-c-553) (EC 1.2.2.3) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are formate and ferricytochrome c-553, whereas its two products are CO₂ and ferrocytochrome c-553.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with a cytochrome as acceptor. The systematic name of this enzyme class is formate:ferricytochrome-c-553 oxidoreductase.