 | ||
Flestolol is a short-acting beta adrenergic receptor antagonist.
Synthesis
Acylation of glycidol (2) with the acid chloride 1 produces the ester 3. Reaction of that intermediate with amine 4, obtained by reaction of 1,1-dimethylethylenediamine with urea, gives flestolol (5).
References
Flestolol Wikipedia(Text) CC BY-SA