Filippini is an Italian surname. Notable people with the surname include:
Francesco Filippini (1853–1895), Italian painterAlberto Filippini (born 1987) Italian footballerAndré Filippini (1924–2013), Swiss bobsledderAntonio Filippini (born 1973), Italian footballerBruno Filippini (born 1945), Italian singerEmanuele Filippini (born 1973), Italian footballerGino Filippini (1900–1962), Italian composerLucy Filippini (1672–1732), Italian saintMarcelo Filippini (born 1967), Uruguayan tennis playerMarco Filippini, (born 1988) Italian footballer