Fasano is an Italian surname. Notable people with the surname include:
Alessio Fasano, Italian pediatric gastroenterologist
Anthony Fasano (born 1984), American football tight-end
Clara Fasano (1900–1990), Italian-born American sculptor
Joseph Fasano (born 1982), poet
Len Fasano, American politician
Mike Fasano, rock drummer
Mike Fasano (politician) (born 1958), state politician in Florida
Sal Fasano (born 1971), American baseball catcher