Farnesol dehydrogenase

In enzymology, a farnesol dehydrogenase (EC 1.1.1.216) is an enzyme that catalyzes the chemical reaction

2-trans,6-trans-farnesol + NADP⁺ ⇌ 2-trans,6-trans-farnesal + NADPH + H⁺

Thus, the two substrates of this enzyme are 2-trans,6-trans-farnesol and NADP⁺, whereas its 3 products are 2-trans,6-trans-farnesal, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 2-trans,6-trans-farnesol:NADP⁺ 1-oxidoreductase. Other names in common use include NADP⁺-farnesol dehydrogenase, and farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase.