Farghānī (Persian: فرغانی, meaning from Farghāna), or Al-Farghani is a common surname in Central and Western Asia and was a common nisbat in the medieval Islamic world. It may refer to the following:
Ahmad ibn Muhammad ibn Kathīr al-Farghānī, also known as Alfraganus, a 9th-century astronomerRustum ibn Bardu al-Farghani, 10th-century Abbasid commander and governor of TarsusSayf-i Farghānī, a 13th-century Persian poetSaʿīd-al-dīn Moḥammad Farghānī, a 13th-century Sufi authorAbu Abdullah b. Ahmad b. Ja'far al-Farghani, the student of al-Tabari who wrote the appendix, al-Sila, to History of the Prophets and Kings.