Species Human Entrez 8880 | Human Mouse Ensembl ENSG00000162613 | |
Aliases FUBP1, FBP, FUBP, hDH V, far upstream element binding protein 1 External IDs MGI: 1196294 HomoloGene: 48253 GeneCards: FUBP1 |
Far upstream element-binding protein 1 is a protein that in humans is encoded by the FUBP1 gene.
This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase.
Interactions
Far upstream element-binding protein 1 has been shown to interact with MAPK14 and SMN1.
References
Far upstream element-binding protein 1 Wikipedia(Text) CC BY-SA