Suvarna Garge (Editor)

FUT8

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Covid-19
Aliases  FUT8
Human  Mouse
Ensembl  ENSG00000033170
Species  Human
Entrez  2530
FUT8
External IDs  MGI: 1858901 HomoloGene: 9650 GeneCards: FUT8

Alpha-(1,6)-fucosyltransferase is an enzyme that in humans is encoded by the FUT8 gene.

This enzyme belongs to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternatively spliced variants encoding different isoforms have been identified.

References

FUT8 Wikipedia


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