Entrez 3171 | Ensembl ENSG00000170608 | |
Aliases FOXA3, FKHH3, HNF3G, TCF3G, forkhead box A3 External IDs MGI: 1347477 HomoloGene: 3308 GeneCards: FOXA3 |
Hepatocyte nuclear factor 3-gamma (HNF-3G), also known as forkhead box protein A3 (FOXA3) or transcription factor 3G (TCF-3G) is a protein that in humans is encoded by the FOXA3 gene.
Function
HNF-3G is a member of the forkheadclass of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.
References
FOXA3 Wikipedia(Text) CC BY-SA