PubChem CID 44158960 Molar mass 492.008 | Formula C28H30ClN3O3 3D model (Jmol) Interactive image | |
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FGI-104 is the name for a family of chemical compounds that act as broad-spectrum antiviral drugs, with activity against a range of viruses including Hepatitis B, Hepatitis C, HIV, Ebola virus and Venezuelan equine encephalitis virus. Compound R19 is the most preferred compound listed in the patent covering this family.
Mechanism
The FGI-104 family of compounds act by inhibiting the protein TSG101, which transports newly replicated viruses to the exterior of an infected cell, and is required by many viruses to reinfect other cells. In pre-clinical studies FGI-104 has been shown to protect mice from Ebola virus disease.
References
FGI-104 Wikipedia(Text) CC BY-SA