Suvarna Garge (Editor)

FBXW10

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Species
  
Entrez
  
10517

Human
  
Ensembl
  
ENSG00000171931

Aliases
  
FBXW10, Fbw10, HREP, SM25H2, SM2SH2, F-box and WD repeat domain containing 10

External IDs
  
MGI: 3052463 HomoloGene: 32757 GeneCards: FBXW10

F-box/WD repeat-containing protein 10 is a protein that in humans is encoded by the FBXW10 gene.

Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004).[supplied by OMIM]

References

FBXW10 Wikipedia


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