Entrez 10517 | Ensembl ENSG00000171931 | |
Aliases FBXW10, Fbw10, HREP, SM25H2, SM2SH2, F-box and WD repeat domain containing 10 External IDs MGI: 3052463 HomoloGene: 32757 GeneCards: FBXW10 |
F-box/WD repeat-containing protein 10 is a protein that in humans is encoded by the FBXW10 gene.
Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004).[supplied by OMIM]
References
FBXW10 Wikipedia(Text) CC BY-SA