Estriol succinate

Estriol succinate (INN) (brand names Sinapause, Styptanon, Synapasa, Synapausa, Synapause, Hemostyptanon, Orgastyptin, Ovestin, Evalon), or oestriol succinate (BAN), also known as estriol disuccinate or estriol hemisuccinate, as well as estriol 16α,17β-di(hydrogen succinate), is a semisynthetic, steroidal estrogen that is marketed in Europe, Hong Kong, and Mexico and was introduced in 1966. It is an estrogen ester, specifically, an ester of estriol. The drug is described as a weak estrogen (relative to estradiol valerate, which is described as a strong estrogen). It was introduced in 1966 and is used in the treatment of menopausal symptoms. The drug is also available in sodium salt form as oestriol sodium succinate (BAN) (brand names Pausan, Styptanon).