Suvarna Garge (Editor)

Estramustine

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
CAS Number
  
2998-57-4

ChemSpider
  
227635

KEGG
  
D04066

PubChem CID
  
259331

UNII
  
35LT29625A

Molar mass
  
440.405 g/mol

Estramustine httpsuploadwikimediaorgwikipediacommonsthu

Synonyms
  
Leo 275; Ro 21-8837; Estradiol 3-(bis(2-chloroethyl)carbamate) ester; Estra-1,3,5(10)-triene-3,17β-diol 3-(bis(2-chloroethyl)carbamate) ester

Estramustine (INN, USAN, BAN) is a synthetic steroidal estrogen and alkylating antineoplastic agent that was never marketed. It is an estrogen ester – specifically, the C3 normustine ester of estradiol – and acts as a prodrug to estradiol and normustine in the body. Estramustine phosphate, the C17β phosphate ester of estramustine, is marketed and used in the treatment of prostate cancer.

References

Estramustine Wikipedia


Similar Topics