Routes of
administration Intramuscular CAS Number 113-38-2 Route Intramuscular injection | ATC code None Molar mass 384.509 g/mol | |
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Trade names Agofollin, Di-Ovocyclin, Progynon DP Legal status In general: ℞ (Prescription only) Synonyms 17β-Estradiol-3,17-dipropionate; Estra-1,3,5(10)-triene-3,17β-diol, 3,17β-dipropanoate | ||
Estradiol dipropionate (BAN, JAN) (brand names Agofollin, Di-Ovocyclin, Progynon DP, others) is a semisynthetic, steroidal estrogen that is or has been marketed in the United States and Europe. It is the 3,17β-dipropanoyl ester of estradiol. Along with estradiol benzoate, estradiol dipropionate was one of the first estradiol esters to be developed, having been patented in 1937, was assessed in clinical studies by 1939, and has been marketed by Schering as Progynon DP and Ciba Pharmaceutical Products as Di-Ovocylin since at least 1940. Relative to estradiol benzoate, estradiol dipropionate has enhanced and very prolonged effects. Prior to the development and introduction of estradiol valerate and estradiol cypionate in the 1950s, estradiol dipropionate and estradiol benzoate were the most widely used estradiol esters.