Estienne is a French surname or given name which may refer to:
Surname:
Henri Estienne (elder) (died 1521), founder of a family of scholars and printers
Robert Estienne (1503–1559), French printer and classical scholar, son of the above
Henri Estienne (1528 or 1531–1598), also known as Henricus Stephanus, French printer and classical scholar, son of Robert Estienne
Charles Estienne (1504–1564), an early exponent of the science of anatomy in France, son of Henri Estienne
Nicole Estienne (c. 1542-c. 1588), French poet, daughter of Charles Estienne
Jean Baptiste Eugène Estienne (1860-1936), French general of artillery and the creator of the French tank arm
Georges Estienne (1896-1969), French aviator, explorer of the Sahara and businessman, son of the general
Given name:
Estienne or Étienne de La Boétie (1530-1563), French philosopher, judge and writer
Estienne Grossin (fl. 1418–1421), French composer
Estienne de La Roche (1470–1530), French mathematician
Estienne Roger (1665 or 1666-1722), French-born printer and publisher working in the Netherlands
Estienne du Tertre (fl. mid-16th century), French composer