Espinosa or Espinoza is a Spanish and Portuguese surname.
Notable people with the surname include:
Juan Bautista de Espinosa (1590–1641), Spanish painter
Jerónimo Jacinto de Espinosa (1600–1667), Spanish painter
Juan de Espinosa Medrano (ca. 1629–1688), Peruvian cleric
Oscar Espinosa Chepe (1940–2013), Cuban economist and dissident
Al Espinosa (1891–1957), American golfer
Álvaro Espinoza, American baseball coach
Anagabriela Espinoza, Miss International 2009 from Mexico
Andrés Espinosa, Mexican runner
Angel Espinosa, Cuban boxer
Chris Espinosa, senior employee of Apple Inc
Danny Espinosa, American baseball player
Dulce María, Mexican actress musician
Eden Espinosa, American singer and stage actress
Giovanny Espinoza, Ecuadorian footballer
Luis Espinosa, Colombian cyclist
Roger Espinoza, Honduran footballer
Rubén Espinoza, Chilean footballer