The Esopus tribe (pr. es-SOAP-es) was a tribe of Lenape (Delaware) Native Americans who were native to Upstate New York, specifically the region of the Catskill Mountains. Their lands included modern-day Ulster County and Sullivan County, New York.
The tribe fought a series of conflicts against settlers from the New Netherland colony from September 1659 to September 1663, known as the Esopus Wars in and around Kingston, New York. At the conclusion of the conflict, the tribe sold large tracts of land to French Huguenot refugees in New Paltz and other communities.
Descendants of the Esopus tribe now live on the Stockbridge-Munsee reservation in Shawano County, Wisconsin and among the Munsee Delaware of Ontario. Historians believe surviving Esopus joined with the Ramapough Mountain Indians of New Jersey following the wars, as well as some Wappinger people after Kieft's War in 1643.