Escoffier is a surname of French origin. Notable people with the surname include:
Alain Escoffier (1949–1977), French anti-communist activist and martyr
Anne-Marie Escoffier (born 1942), French politician
Auguste Escoffier (1846–1935), French chef, the father of cuisine classique style of haute cuisine
Jean-Yves Escoffier (1950-2003), French cinematographer
Louis-Casimir Escoffier, known as Casimir Ney (1801–1877), French composer and violist