Escher is a surname. Notable people with the surname include:
Alfred Escher (1819−1883), a Swiss politician and railway pioneer
Arnold Escher von der Linth (1807−1872), a Swiss geologist
Arthur Escher (born 1928), a Dutch geologist, first ascendent of Puncak Mandala, son of M. C. Escher
Berend George Escher (1885−1967), a Dutch geologist, half-brother of M. C. Escher
George Arnold Escher (1843−1939), a Dutch civil engineer, foreign advisor to Japan, father of M. C. Escher
Gitta Escher (born 1957), a German gymnast
Hans Caspar Escher (1775–1859), a Swiss industrialist and co-founder of Escher Wyss AG
Hans Conrad Escher von der Linth (1767−1823), a Swiss scientist, civil engineer and politician
Hans Conrad Escher (vom Luchs) (1743−1814), a Swiss politician
Heinrich Escher (1626−1710), a Swiss politician, mayor of Zürich
Josef Escher (1885−1954), a Swiss Federal Councilor
Luiz Jeferson Escher (born 1987), Brazilian footballer
Lydia Escher (1858−1891), a Swiss patron of the arts
M. C. Escher, Maurits Cornelis Escher (1898−1972), a Dutch graphic artist
Rudolf George Escher (1912−1980), a Dutch composer and music theoretician
Sandra Escher (born 1945), a Dutch psychiatrist
William J. D. Escher (1931–2014), an American aerospace engineer
