Ephedrine dehydrogenase

In enzymology, an ephedrine dehydrogenase (EC 1.5.1.18) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are (-)-ephedrine and NAD⁺, whereas its 3 products are (R)-2-methylimino-1-phenylpropan-1-ol, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (-)-ephedrine:NAD+ 2-oxidoreductase.