Entwistle is an English surname. Notable people with the surname include:
Alan Entwistle, British scholar
Bobby Entwistle, English footballer
Cyril Entwistle, British politician
Darren Entwistle, Canadian businessman
Edward Entwistle, English railroad engineer
George Entwistle, British television producer
Harry Entwistle, English-born Australian priest
James F. Entwistle, American diplomat
John Entwistle, the original bass guitarist of The Who
Jonty Entwistle, English footballer
Neil Entwistle, convicted of the murder of his wife and daughter
Noel Entwistle, UK educational psychologist
Peg Entwistle, British actress
Robert Entwistle, English cricketer
Vicky Entwistle, British actress
Wayne Entwistle, English footballer
