Ent pimara 9(11),15 diene synthase

Ent-pimara-9(11),15-diene synthase (EC 4.2.3.31, PMD synthase) is an enzyme with systematic name ent-copalyl-diphosphate diphosphate-lyase (ent-pimara-9(11),15-diene-forming). This enzyme catalyses the following chemical reaction

ent-copalyl diphosphate ⇌ ent-pimara-9(11),15-diene + diphosphate

This enzyme is involved in the biosynthesis of the diterpenoid viguiepinol and requires Mg²⁺, Co²⁺, Zn²⁺ or Ni²⁺ for activity.