Enomoto (written: 榎本) is a Japanese surname. Notable people with the surname include:
Aoi Enomoto (榎本 葵, born 1992), Japanese baseball playerAtsuko Enomoto (榎本 温子, born 1979), Japanese voice actress and singerAyako Enomoto (榎本 亜弥子, born 1985), Japanese model and actressDaisuke Enomoto (榎本 大輔, born 1971), Japanese business executive and space touristJun Enomoto (榎本 潤, born 1977), Japanese footballerKanako Enomoto (榎本 加奈子, born 1980), Japanese actressKenichi Enomoto (榎本 健一, 1904–1970), Japanese comedianKurumi Enomoto (榎本 くるみ, born 1981), Japanese singer-songwriterNariko Enomoto (榎本 ナリコ, born 1967), Japanese manga artistEnomoto Seifu (榎本 星布, 1732–1815), Japanese poetShunji Enomoto (榎本 俊二, born 1968), Japanese manga artistEnomoto Takeaki (榎本 武揚, 1836–1908), Japanese samurai and Imperial Japanese Navy admiralTatsuya Enomoto (榎本 達也, born 1979), Japanese footballerTetsuya Enomoto (榎本 哲也, born 1983), Japanese footballerYasubey Enomoto (born 1983), Swiss mixed martial artist