Enomoto (written: 榎本) is a Japanese surname. Notable people with the surname include:
Aoi Enomoto (榎本 葵, born 1992), Japanese baseball player
Atsuko Enomoto (榎本 温子, born 1979), Japanese voice actress and singer
Ayako Enomoto (榎本 亜弥子, born 1985), Japanese model and actress
Daisuke Enomoto (榎本 大輔, born 1971), Japanese business executive and space tourist
Jun Enomoto (榎本 潤, born 1977), Japanese footballer
Kanako Enomoto (榎本 加奈子, born 1980), Japanese actress
Kenichi Enomoto (榎本 健一, 1904–1970), Japanese comedian
Kurumi Enomoto (榎本 くるみ, born 1981), Japanese singer-songwriter
Nariko Enomoto (榎本 ナリコ, born 1967), Japanese manga artist
Enomoto Seifu (榎本 星布, 1732–1815), Japanese poet
Shunji Enomoto (榎本 俊二, born 1968), Japanese manga artist
Enomoto Takeaki (榎本 武揚, 1836–1908), Japanese samurai and Imperial Japanese Navy admiral
Tatsuya Enomoto (榎本 達也, born 1979), Japanese footballer
Tetsuya Enomoto (榎本 哲也, born 1983), Japanese footballer
Yasubey Enomoto (born 1983), Swiss mixed martial artist
