Kalpana Kalpana (Editor)

Emylcamate

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ATC code
  
N05BC03 (WHO)

PubChem CID
  
6526

UNII
  
KCJ747D3R4

CAS ID
  
78-28-4

CAS Number
  
78-28-4

ChemSpider
  
6278

KEGG
  
D07317

Emylcamate

Emylcamate (marketed as Striatran by Merck) is an anxiolytic and muscle relaxant. It was patented in the US in 1961 (US Patent 2,972,564) and advertised for the treatment of anxiety and tension. It was claimed to be superior to meprobamate, which was the market leader at the time. It is no longer prescribed.

A study of the drug's effects in mice was done in 1959. It concluded that at 50 mg/kg emylcamate gave a 63% decrease in motor activity compared to meprobamate's 32% decrease, a doubling in effective potency. The therapeutic index in mice was also established:

Emylcamate also has a faster intra-parenteral onset then meprobabamate, 3 minutes compared to 35.

References

Emylcamate Wikipedia