Girish Mahajan (Editor)

Elsilimomab

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Type
  
Whole antibody

Target
  
IL-6

CAS Number
  
468715-71-1

Source
  
Mouse

ATC code
  
none

ChemSpider
  
none

Elsilimomab (also known as B-E8) is a mouse monoclonal antibody and an immunosuppressive drug.

It (OPR-003) targets (and blocks) Interleukin-6.

It has undergone a number of early stage clinical trails, e.g. for lymphoma and myeloma.

It was used as a template to develop a high-affinity, antagonist, fully human anti-IL-6 mAb 1339.

References

Elsilimomab Wikipedia