Ekholm is a Swedish surname. Notable people with the surname include:
Berndt Ekholm (born 1944), Swedish Social Democratic politician
Helena Ekholm (born 1984), Swedish biathlete
Jan Ekholm (born 1969), Swedish football (soccer) goalkeeper
Jan-Olof Ekholm (born 1931), Swedish detective fiction writer
Kaarlo Ekholm (1884–1946), Finnish gymnast who competed in the 1912 Summer Olympics
Mattias Ekholm (born 1990), Swedish ice hockey player
Nancy Ekholm Burkert (born 1933), American artist and illustrator
Nils Gustaf Ekholm (1848–1923), Swedish meteorologist