Eisenberg is a German surname with the meaning "iron mountain". Notable people with the surname include:
Arlene Eisenberg (1934-2003), American author
Arlo Eisenberg, American aggressive inline skater
Aron Eisenberg, American actor
Billy Eisenberg, American bridge and backgammon player
David Eisenberg, American biochemist
Hallie Kate Eisenberg, American actress
Howard Eisenberg, American author
Jacob Eisenberg (musician), American pianist, author and teacher
Jesse Eisenberg, American actor
Jewlia Eisenberg, American musician, vocalist, and composer
José Eisenberg, Italian entrepreneur and founder of Eisenberg Paris
Josy Eisenberg, French animator of television and co-scenarist of the movie Rabbi Jacob
Leon Eisenberg, child psychiatrist, social psychiatrist and medical educator
Louis Eisenberg, chess master
Matthias Eisenberg, German organist
Ned Eisenberg, American actor
Ruth Brewer Eisenberg, "Ivory" of inter-racial piano duo, Ebony and Ivory
Susan Eisenberg, American voice actress
There is also Joanna Aizenberg, a Russian-born chemist and biomimetics expert; this is the English transliteration of the Russian transliteration of Eisenberg, Айзенберг.