Eden's Trail is a 5 issues Marvel Comics limited series created in 2003 by Chuck Austen and Steve Uy. The story focuses on a young woman named Tila and a man named Latch who's immortal and seeks a way to rid himself of his immortality. Steve Uy has stated his disdain for the series, as he had little control of the story.
References
Eden's Trail Wikipedia(Text) CC BY-SA