Girish Mahajan


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Species  Human
Entrez  55770
Human  Mouse
Ensembl  ENSG00000112685
Aliases  EXOC2, SEC5, SEC5L1, Sec5p, exocyst complex component 2
External IDs  MGI: 1913732 HomoloGene: 10122 GeneCards: EXOC2

Exocyst complex component 2 is a protein that in humans is encoded by the EXOC2 gene.

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts.


EXOC2 Wikipedia

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