The twelfth season of the American fictional drama television series ER first aired on September 22, 2005 and concluded on May 18, 2006. It consists of 22 episodes.
Kovac and Abby become the main central characters and their relationship slowly starts to get back on track as they deal with her unexpected pregnancy. A new nurse manager causes friction among the staff, following a successful operation Weaver no longer needs her cane, Pratt journeys to Africa where he joins Carter on a relief mission while a face from Sam's past leaves the lives of Abby and Kovac hanging in the balance.
Following Sherry Stringfield's departure in the season premiere, this season becomes the first to not feature any of the original cast members.
Main cast
Goran Visnjic as Dr. Luka Kovač, Attending Physician / Chief of Emergency Medicine
Maura Tierney as Dr. Abby Lockhart, Second Year Resident
Mekhi Phifer as Dr. Greg Pratt, Fourth Year Resident
Sherry Stringfield as Dr. Susan Lewis, Chief of Emergency Medicine (outgoing)
Parminder Nagra as Dr. Neela Rasgotra, Second Year Resident
Linda Cardellini as Nurse Samantha Taggart
Shane West as Dr. Ray Barnett, Second Year Resident
Scott Grimes as Dr. Archie Morris, Chief Resident
Laura Innes as Dr. Kerry Weaver, Chief of Staff
Doctors and medical students
John Leguizamo as Dr. Victor Clemente, Attending Physician
Amy Aquino as Dr. Janet Coburn, Chief of Obstetrics and Gynecology
John Aylward as Dr. Donald Anspaugh, Surgical Attending Physician and Hospital Board Member
Leland Orser as Dr. Lucien Dubenko, Chief of Surgery
Sara Gilbert as Dr. Jane Figler, ER Intern
Michael Buchman Silver as Dr. Paul Myers, Psychiatrist
Dahlia Salem as Dr. Jessica Albright, Surgical Chief Resident
Anthony Giangrande as Dr. Jeremy Munson, ER Intern
Michael Spellman as Dr. Jim Babinski, ER Intern
Britain Spellings as Dr. Sackowitz
Corey Stoll as Dr. Teddy Marsh, Intern
Damali Scott as Dr. Lana Clemons, Intern
Nurses
Kristen Johnston as Nurse Manager Eve Peyton
Deezer D as Nurse Malik McGrath
Laura Cerón as Nurse Chuny Marquez
Yvette Freeman as Nurse Haleh Adams
Lily Mariye as Nurse Lily Jarvik
Dinah Lenney as Nurse Shirley
April Lee Hernandez as Nurse Inez
Kyle Richards as Nurse Dori
Liza Del Mundo as Nurse Severa
Nadia Shazana as OR Nurse Jacy
Staff and paramedics
John Stamos as Paramedic Tony Gates
Abraham Benrubi as Desk Clerk Jerry Markovic
Troy Evans as Desk Clerk Frank Martin
Emily Wagner as Paramedic Doris Pickman
Monte Russell as Paramedic Zadro White
Lyn. A Henderson as Paramedic Pamela Olbes
Demitrius Navarro as Paramedic Morales
Brian Lester as Paramedic Brian Dumar
Louie Liberti as Paramedic Bardelli
Family
Danny Glover as Charlie Pratt, Greg Pratt's father
Noah Wyle as Dr. John Carter (in Darfur)
Sharif Atkins as Dr. Michael Gallant (in Iraq)
Mary McCormack as Debbie (in Darfur)
Eamonn Walker as Dr. Steven Dakarai (in Darfur)
Kat Dennings as Zoe Butler
Serena Williams as Alice Watson