Suvarna Garge

ENTPD1

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Species  Human
Entrez  953
Human  Mouse
Ensembl  n/a
ENTPD1 wwwbiolegendcommediaassetsproductsproductim
Aliases  ENTPD1, ATPDase, CD39, NTPDase-1, SPG64, ectonucleoside triphosphate diphosphohydrolase 1
External IDs  MGI: 102805 HomoloGene: 20423 GeneCards: ENTPD1

Gene music using protein sequence of entpd1 ectonucleoside triphosphate diphosphohydrolase 1


Ectonucleoside triphosphate diphosphohydrolase-1 (gene: ENTPD1; protein: NTPDase1) also known as CD39 (Cluster of Differentiation 39), is a typical cell surface-located enzymes with an extracellularly facing catalytic site. NTPDase1 is an ectonucleotidase that catalyse the hydrolysis of γ- and β-phosphate residues of triphospho- and diphosphonucleosides to the monophosphonucleoside derivative. For example, NTPDase1 hydrolyzes P2 receptor ligands, namely ATP, ADP, UTP and UDP with similar efficacy. NTPDase1 can therefore affect P2 receptor activation and functions.

References

ENTPD1 Wikipedia


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