EIF2C2

Updated on Dec 11, 2024

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Species Human Entrez 27161		Human Mouse Ensembl ENSG00000123908

Aliases AGO2, EIF2C2, Q10, argonaute 2, RISC catalytic component External IDs MGI: 2446632 HomoloGene: 81825 GeneCards: AGO2

Protein argonaute-2 is a protein that in humans is encoded by the EIF2C2 gene.

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with Dicer1 and play a role in short-interfering-RNA-mediated gene silencing.

Interactions

EIF2C2 has been shown to interact with

DDX20,

DICER1,

FMRP, FXR1P, FXR2P, and

TNRC6B.

References

EIF2C2 Wikipedia

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