Harman Patil (Editor)

EIF2C2

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Species
  
Human

Entrez
  
27161

Human
  
Mouse

Ensembl
  
ENSG00000123908

EIF2C2

Aliases
  
AGO2, EIF2C2, Q10, argonaute 2, RISC catalytic component

External IDs
  
MGI: 2446632 HomoloGene: 81825 GeneCards: AGO2

Protein argonaute-2 is a protein that in humans is encoded by the EIF2C2 gene.

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with Dicer1 and play a role in short-interfering-RNA-mediated gene silencing.

Interactions

EIF2C2 has been shown to interact with

  • DDX20,
  • DICER1,
  • FMRP, FXR1P, FXR2P, and
  • TNRC6B.
  • References

    EIF2C2 Wikipedia