Harman Patil


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Species  Human
Entrez  1959
Human  Mouse
Ensembl  ENSG00000122877
Aliases  EGR2, AT591, CMT1D, CMT4E, KROX20, early growth response 2
External IDs  MGI: 95296 HomoloGene: 20123 GeneCards: EGR2

Early growth response protein 2 is a protein that in humans is encoded by the EGR2 gene.


The early growth response protein 2 is a transcription factor with three tandem C2H2-type zinc fingers. Mutations in this gene are associated with the autosomal dominant Charcot-Marie-Tooth disease, type 1D, Dejerine–Sottas disease, and Congenital Hypomyelinating Neuropathy. Two studies have linked EGR2 expression to proliferation of osteoprogenitors and cell lines derived from Ewing sarcoma, which is a highly aggressive bone-associated cancer.


EGR2 Wikipedia

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