Samiksha Jaiswal

EGLN2

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Species  Human
Entrez  112398
Human  Mouse
Ensembl  ENSG00000269858
EGLN2
Aliases  EGLN2, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1, egl-9 family hypoxia inducible factor 2
External IDs  MGI: 1932287 HomoloGene: 14204 GeneCards: EGLN2

Egl nine homolog 2 is a protein that in humans is encoded by the EGLN2 gene.

The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degradation by prolyl hydroxylation. This gene encodes an enzyme responsible for this posttranslational modification. Multiple alternatively spliced variants, encoding the same protein, have been identified.

References

EGLN2 Wikipedia


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