Dumitrescu is a Romanian surname. Notable people with the surname include:
Alexandru Dumitrescu, sprint canoerConstantin Dumitrescu (born 1931), boxerConstantin Ticu Dumitrescu (1928–2008), politicianCristian Dumitrescu (born 1955), politicianDaniel Dumitrescu (born 1968), boxerGeo Dumitrescu, poet and journalistGeorge Dumitrescu, poetGeorge Dorul Dumitrescu, prose writerIancu Dumitrescu (born 1944), avant-garde composerIlie Dumitrescu (born 1969), soccer playerIon Dumitrescu (1925–1999), sports shooter and Olympic championLiana Dumitrescu (1973–2011), politicianNelu Dumitrescu, drummerNatalia Dumitrescu, abstract painterPetre Dumitrescu (1882–1950), generalRăzvan Dumitrescu, journalistRuxandra Dumitrescu, volleyball playerSava Dumitrescu, pharmacologist and professorVasile Dumitrescu, bobsledderVictor Dumitrescu (1924–1997), soccer playerZamfir Dumitrescu (born 1946), painterZoe Dumitrescu-Bușulenga, literary critic and philosopher