Trade names No-Spa, Droteva 80 Molar mass 397.507 g/mol | ATC code A03AD02 (WHO) | |
 | ||
AHFS/Drugs.com International Drug Names Routes ofadministration Oral, intravenous, intramuscular Legal status OTC (tablets), ℞-only (solution for injection) (RU) Bioavailability Highly variable (~65%), peak at 45–60 min | ||
Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, used to enhance cervical dilation during childbirth.
It is structurally related to papaverine, is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects.
It is available in Asian and Eastern European countries under several brand names, with No-Spa being one of them.
An article from 2013 described the effects from overdose (in a 19-year-old woman) as including vomiting, seizures and fatal cardiac toxicity.
In 2016, the young Russian chess player Ivan Bukavshin died of a massive overdose (or poisoning) of the drug, which was originally thought to be a stroke.
Drotaverine hydrochloride is effective and safe in children with recurrent abdominal pain
References
Drotaverine Wikipedia(Text) CC BY-SA