Rahul Sharma (Editor)

Donitriptan

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ATC code
  
None

CAS Number
  
170912-52-4

ChemSpider
  
171128

Molar mass
  
403.477 g/mol

Legal status
  
Never marketed

PubChem CID
  
197706

UNII
  
70968BVH2J

Donitriptan httpsuploadwikimediaorgwikipediacommonsthu

Donitriptan (INN) (code name F-11356) is a triptan drug which was investigated as an antimigraine agent but ultimately was never marketed. It acts as a high-affinity, high-efficacy/near-full agonist of the 5-HT1B (pKi = 9.4–10.1; IA = 94%) and 5-HT1D receptors (pKi = 9.3–10.2; IA = 97%), and is among the most potent of the triptan series of drugs. Donitriptan was being developed in France by bioMérieux-Pierre Fabre and made it to phase II clinical trials in Europe before development was discontinued.

References

Donitriptan Wikipedia
(Text) CC BY-SA