Domingues is a surname. Notable people with the surname include:
Adauto Domingues (born 1961), Brazilian middle-distance runner
Adelina Domingues (1888–2002), American supercentenarian
Altino Domingues (born 1951), Portuguese-American football player
Amy Domingues, cellist and viola da gamba player
João Domingues (born 1993), Portuguese tennis player
Leandro Domingues (born 1983), Brazilian footballer
Maurício Rodrigues Alves Domingues (born 1978), Brazilian football player
Renan Cardoso Domingues (born 1988), Brazilian football player
