The Disease Ontology (DO) is a formal ontology of human disease. The Disease Ontology project is hosted at the Institute for Genome Sciences at the University of Maryland School of Medicine.
The Disease Ontology project was initially developed in 2003 at Northwestern University to address the need for a purpose-built ontology that covers the full spectrum of disease concepts annotated within biomedical repositories within an ontological framework that is extensible to meet community needs.
The Disease Ontology is an OBO (Open Biomedical Ontologies) Foundry ontology.
Disease Ontology Identifiers (DOIDs) consist of the prefix DOID: followed by number, for example, Alzheimer's disease has the stable identifier DOID:10652.
Example term
The Disease Ontology entry for motor neuron disease in OBO format is given below, showing the links to other classification schemes, including ICD-9, ICD-10, MeSH, SNOMED and UMLS.
id: DOID:231 name: motor neuron disease def: "A neurodegenerative disease that is located_in the motor neurones." Motor neuron disease xref: ICD10CM:G12.2 xref: ICD10CM:G12.20 xref: ICD9CM:335.2 xref: MSH:D016472 xref: SNOMEDCT_US_2016_03_01:155015007 xref: SNOMEDCT_US_2016_03_01:192888001 xref: SNOMEDCT_US_2016_03_01:192889009 xref: SNOMEDCT_US_2016_03_01:192890000 xref: SNOMEDCT_US_2016_03_01:37340000 xref: UMLS_CUI:C0085084 is_a: DOID:1289 ! neurodegenerative disease