Dimethylglycine N methyltransferase

Dimethylglycine N-methyltransferase (EC 2.1.1.161, BsmB, DMT) is an enzyme with systematic name S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase (betaine-forming). This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + N,N-dimethylglycine ⇌ S-adenosyl-L-homocysteine + betaine

This enzyme is purified from the marine cyanobacterium Synechococcus sp. WH8102.