Dihydrochelirubine 12 monooxygenase

In enzymology, a dihydrochelirubine 12-monooxygenase (EC 1.14.13.57) is an enzyme that catalyzes the chemical reaction

dihydrochelirubine + NADPH + H⁺ + O₂ ⇌ 12-hydroxydihydrochelirubine + NADP⁺ + H₂O

The 4 substrates of this enzyme are dihydrochelirubine, NADPH, H⁺, and O₂, whereas its 3 products are 12-hydroxydihydrochelirubine, NADP⁺, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is dihydrochelirubine,NADPH:oxygen oxidoreductase (12-hydroxylating). This enzyme is also called dihydrochelirubine 12-hydroxylase. This enzyme participates in alkaloid biosynthesis i.