Dibenzothiophene dihydrodiol dehydrogenase

In enzymology, a dibenzothiophene dihydrodiol dehydrogenase (EC 1.3.1.60) is an enzyme that catalyzes the chemical reaction

cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD⁺ ⇌ 1,2-dihydroxydibenzothiophene + NADH + H⁺

Thus, the two substrates of this enzyme are cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene and NAD⁺, whereas its 3 products are 1,2-dihydroxydibenzothiophene, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene:NAD+ oxidoreductase.