Trisha Shetty (Editor)

Diacetyl reductase ((S) acetoin forming)

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EC number  1.1.1.304
BRENDA  BRENDA entry
KEGG  KEGG entry
IntEnz  IntEnz view
ExPASy  NiceZyme view
MetaCyc  metabolic pathway

Diacetyl reductase ((S)-acetoin forming) (EC 1.1.1.304, (S)-acetoin dehydrogenase) is an enzyme with systematic name (S)-acetoin:NAD+ oxidoreductase. This enzyme catalyses the following chemical reaction

(S)-acetoin + NAD+ diacetyl + NADH + H+

The reaction is catalysed in the reverse direction. This activity is usually associated with butanediol dehydrogenase activity (EC 1.1.1.4 or EC 1.1.1.76). While the butanediol dehydrogenase activity is reversible, diacetyl reductase activity is irreversible. This enzyme has been reported in the bacteria Geobacillus stearothermophilus, Enterobacter aerogenes and Klebsiella pneumoniae. Different from EC 1.1.1.303, diacetyl reductase ((R)-acetoin forming).

References

Diacetyl reductase ((S)-acetoin forming) Wikipedia


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