Desjardins (French, of the gardens) is a common last name in French-speaking Canada and is the name of:
Alphonse Desjardins (co-operator), co-founder of the Caisses populaires Desjardins (today Desjardins Group), a forerunner of North American credit unions
Andrew Desjardins (born 1986), Canadian professional ice hockey player
Cédrick Desjardins (born 1985), Canadian professional ice hockey goaltender
Dorimène Roy Desjardins, co-founder of the Caisses populaires Desjardins
Éric Desjardins (born 1969), Canadian professional ice hockey player
Jacques Guérin-Desjardins
Julien François Desjardins (1799-1840), French zoologist
Marie-Catherine Desjardins (1640-1683), usually referred to as Marie-Catherine de Villedieu, a 17th-century French author
Martin Desjardins, French sculptor
Pete Desjardins, American diver, participated in 1924 and 1928 Summer Olympics
Richard Desjardins, singer-songwriter, actor, and documentary film maker from the Canadian province of Quebec