Girish Mahajan (Editor)

Dermatan 4 sulfotransferase

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EC number  2.8.2.35
BRENDA  BRENDA entry
KEGG  KEGG entry
IntEnz  IntEnz view
ExPASy  NiceZyme view
MetaCyc  metabolic pathway

Dermatan 4-sulfotransferase (EC 2.8.2.35, dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase, dermatan-4-sulfotransferase-1, dermatan-4-sulfotransferase 1, D4ST-1, dermatan N-acetylgalactosamine 4-O-sulfotransferase, CHST14 protein, CHST14) is an enzyme with systematic name 3'-phospho-5'-adenylyl sulfate:(dermatan)-N-acetyl-D-galactosamine 4-sulfotransferase. This enzyme catalyses the following chemical reaction

3'-phospho-5'-adenylyl sulfate + [dermatan]-N-acetyl-D-galactosamine adenosine 3',5'-bisphosphate + [dermatan]-4-O-sulfo-N-acetyl-D-galactosamine

The sulfation takes place at the 4-position of N-acetyl-D-galactosamine residues of dermatan.

References

Dermatan 4-sulfotransferase Wikipedia


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