Derek Williams may refer to:
Derek Williams (footballer, born 1922), English footballer for Chester City
Derek Williams (footballer, born 1937), English footballer for Grimsby Town
Derek Williams (Welsh footballer) (1934–2014), Welsh footballer
Derek Williams (rugby player) (1924–2014), former Welsh international rugby union player
Derek Williams (filmmaker) (born 1929), British documentary film director and writer
Derek Williams (boxer) (born 1965), English heavyweight boxer of the 1980s and 1990s
Derek Williams (art collector) (1929–1984), Welsh collector of modern art
