Supriya Ghosh (Editor)

Dephospho CoA kinase

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EC number
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  9026-83-9
KEGG  KEGG entry

In enzymology, a dephospho-CoA kinase (EC is an enzyme that catalyzes the chemical reaction

ATP + dephospho-CoA ADP + CoA

Thus, the two substrates of this enzyme are ATP and dephospho-CoA, whereas its two products are ADP and CoA.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:dephospho-CoA 3'-phosphotransferase. Other names in common use include dephosphocoenzyme A kinase (phosphorylating), 3'-dephospho-CoA kinase, and dephosphocoenzyme A kinase. This enzyme participates in pantothenate and coa biosynthesis.

Structural studies

As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes 1JJV, 1N3B, 1T3H, 1VHL, 1VHT, 1VIY, 2GRJ, and 2IF2.


Dephospho-CoA kinase Wikipedia